IL-15 (mutant) (human):Fc (human) (rec.)
产品名称: IL-15 (mutant) (human):Fc (human) (rec.)
英文名称:
产品编号: CHI-HF-21015M
产品价格: 0
产品产地: USA
品牌商标: chimerigen
更新时间: null
使用范围: null
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Synonyms : Interleukin-15 Host : CHO cell Sequence : The extracellular domain of human IL-15(NP_751914.1)(Asn49-Ser162)including mutations at Q149D and Q156D is fused to the N-terminus of the Fc region of human IgG1. Molecular Mass : 41 KDa (monomer) Purity : >98%,by SDS-PAGE under reducing conditions. Endotoxin Content : <0.06 EU/μg as determined by LAL test. Activity : This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell proliferation, promotes transplant tolerance, does not activate the STAT -signaling pathway, and exerts a prolonged circulating half-life caused by the modified Fc domain. Formulation : Lyophilized from 0.2μm-filtered solution in PBS. Reconstitution : Reconstitute at 100μg/ml in sterile PBS. Use / Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. Avoid freeze/thaw cycles.