FITC标记的RAS家族关联结构域蛋白8抗体
产品名称： FITC标记的RAS家族关联结构域蛋白8抗体
英文名称： Anti-RASSF8/FITC
产品编号： HZ-6089R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-RASSF8/FITC Conjugated antibody
FITC标记的RAS家族关联结构域蛋白8抗体
| 英文名称 | Anti-RASSF8/FITC |
| 中文名称 | FITC标记的RAS家族关联结构域蛋白8抗体 |
| 别 名 | C12orf2; Carcinoma associated HOJ 1; Carcinoma associated protein HOJ 1; HoJ 1; HoJ1; Ras association (RalGDS/AF 6) domain family (N terminal) member 8; Ras association (RalGDS/AF 6) domain family 8; Ras association domain containing protein 8; Ras association domain family 8; RASSF 8; RASF8_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 48kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RASSF8 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Tissue Specificity: Widely expressed as a 6.2 kb transcript. A 2.2 kb alternatively spliced transcript is expressed exclusively in testis. DISEASE: Note=A chromosomal aberration involving RASSF8 is found in a complex type of synpolydactyly referred to as 3/3-prime/4 synpolydactyly associated with metacarpal and metatarsal synostoses. Reciprocal translocation t(12;22)(p11.2;q13.3) with C12orf2. Similarity: Contains 1 Ras-associating domain. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码肿瘤抑制蛋白的Ras结合域家族（RASSFF）的成员。该基因对于维持上皮细胞的粘附连接功能至关重要，并在上皮细胞迁移中起作用。它是一个肺肿瘤抑制基因候选。染色体易位T（12；22）（P11.2；Q133）导致该基因和FBLN1基因的融合在复杂的多指肌腱中发现。对该基因已发现编码不同亚型的多个交替剪接转录变体。