HGF polyclonal antibody (A01)
产品名称： HGF polyclonal antibody (A01)
英文名称： HGF polyclonal antibody (A01)
产品编号： H00003082-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant HGF.
- Immunogen:
- HGF (NP_000592, 619 a.a. ~ 728 a.a) partial recombinant protein with GST tag.
- Sequence:
- YTGLINYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYKVPQS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Analysis of growth factor expression in affected and unaffected muscles of oculo-pharyngeal muscular dystrophy (OPMD) patients: A pilot study.
Bouazza B, Kratassiouk G, Gjata B, Perie S, Guily JL, Butler-Browne GS, Svinartchouk F.Neuromuscul Disord. 2009 Mar;19(3):199-206. Epub 2009 Jan 29.
- Application Image
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 3082
- GeneBank Accession#:
- NM_000601
- Protein Accession#:
- NP_000592
- Gene Name:
- HGF
- Gene Alias:
- F-TCF,HGFB,HPTA,SF
- Gene Description:
- hepatocyte growth factor (hepapoietin A; scatter factor)
- Omim ID:
- 142409
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq
- Other Designations:
- fibroblast-derived tumor cytotoxic factor,hepatocyte growth factor,hepatopoietin A,lung fibroblast-derived mitogen,scatter factor
- Interactome
- Related Disease
- Amyotrophic Lateral Sclerosis
- Amyotrophic lateral sclerosis
- Anoxia
- Atherosclerosis
- Autistic Disorder
- Birth Weight
- Breast cancer
- Cardiovascular Diseases
- Carotid Artery Diseases
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Hepatitis, Toxic
- Hyperparathyroidism, Secondary
- Hypertension
- Kidney Failure, Chronic