分子量:35.8 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human SULT1B1, His Tag by the LAL method.

Buffer:50 mM Tris, 150 mM NaCl, pH 7.5

生物活性:

产品特性:Human SULT1B1, His Tag is fused with a polyhistidine tag at the N-terminus, and has a calculated MW of 35.8 kDa. The predicted N-terminus is Met. The reducing (R) protein migrates as 35.8 kDa in SDS-PAGE .

产品背景:Sulfotransferase family cytosolic 1B member 1 (SULT1B1) is also known as sulfotransferase 1B2 (ST1B2) and thyroid hormone sulfotransferase, which is an enzyme that in humans is encoded by the SULT1B1 gene. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. Furthermore, sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites.