FITC标记的1号染色体开放阅读框69抗体
产品名称： FITC标记的1号染色体开放阅读框69抗体
英文名称： Anti-C1orf69/FITC
产品编号： HZ-15075R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C1orf69/FITC Conjugated antibody
FITC标记的1号染色体开放阅读框69抗体
| 英文名称 | Anti-C1orf69/FITC |
| 中文名称 | FITC标记的1号染色体开放阅读框69抗体 |
| 别 名 | C1orf69; CA069_HUMAN; CAF17_HUMAN; FLJ12734; FLJ13849; IBA57; IBA57 iron sulfur cluster assembly homolog; IBA57 iron sulfur cluster assembly homolog (S. cerevisiae); Iron sulfur cluster assembly factor for biotin synthase and aconitase like; Iron-sulfur cluster assembly factor homolog; mitochondrial; Mitochondrial proteins with a mass of 57kDa; Putative transferase C1orf69; Putative transferase C1orf69 mitochondrial; Putative transferase CAF17, mitochondrial. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C1orf69 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Function: Required for normal heme biosynthesis (By similarity). Subcellular Location: Mitochondrion (Potential). Similarity: Belongs to the GcvT family. CAF17 subfamily. Database links: UniProtKB/Swiss-Prot: Q5T440.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
C1OFF63属于gcvT家族的CAF17亚家族，是正常血红素合成所需的356氨基酸线粒体蛋白。血红素合成依赖于通过铁硫（FE-S）簇生成器蛋白（如C1OFF9）来接收铁，这是特别被认为组装FE-S簇的线粒体乌头酸酶和脂酸酯合酶。在斑马鱼中，C1OFR9缺乏导致贫血。编码C1OFF66的基因编码到人类1号染色体上，最大的人类染色体跨越2亿6000万个碱基对，占人类基因组的8%。1号染色体上约有3000个基因，考虑到基因数量众多，也出现了大量与1号染色体相关的疾病。