NPHP1 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： NPHP1 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： NPHP1 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00004867-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human NPHP1 protein.
- Immunogen:
- NPHP1 (NP_997064.1, 1 a.a. ~ 121 a.a) full-length human protein.
- Sequence:
- MLARRQRDPLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSKADESAPVANYNQRKEEEHTLLDKLTQQLQGLAVTISRENITEYASFLPFFFLF
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of NPHP1 expression in transfected 293T cell line (H00004867-T01) by NPHP1 MaxPab polyclonal antibody.
Lane 1: NPHP1 transfected lysate(13.31 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 4867
- GeneBank Accession#:
- NM_207181.1
- Protein Accession#:
- NP_997064.1
- Gene Name:
- NPHP1
- Gene Alias:
- FLJ97602,JBTS4,NPH1,SLSN1
- Gene Description:
- nephronophthisis 1 (juvenile)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- nephrocystin-1