DPABH-01339 detects endogenous levels of RSK3 only when phosphorylated at Threonine 353 and Threonine 356.Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. *   http://www.creative-diagnostics.com/Anti-RPS6KA2-PAb-199475-489.htm