目前 ，经过全体公司同仁的不懈努力, 惠研生物技术服务已经参与并支持客户发表SCI文章累计影响因子IF 超过160分！（依据2014年 JCR） （截止2014 08 10）

外显子组测序分析
Activating Mutations in PTPN3 Promote Cholangiocarcinoma Cell Proliferation and Migration and Are Associated With Tumor Recurrence in Patients. Gastroenterology. 2014 May;146(5):1397-407.（IF=11.675）

外显子组测序分析
Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex.Hepatology. (IF= 11.19)

外显子组测序分析
Mutations in POFUT1, Encoding Protein O-fucosyltransferase1,Cause Generalized Dowling-Degos Disease, (2013). Am J Hum Genet. Am J Hum Genet. 2013 (IF= 10.987)

蛋白突变结构建模与功能分析
Exome sequencing identifies SLCO2A1 mutations as a cause of primary hypertrophic osteoarthropathy. Am J Hum Genet. 2012 Jan 13;90(1):125-32. (IF= 10.987)

蛋白突变结构建模与功能分析
Activating Mutations in PTPN3 Promote Cholangiocarcinoma Cell Proliferation and Migration and Are Associated With Tumor Recurrence in Patients. Gastroenterology. 2014 May;146(5):1397-407. (IF 11.675)

miRNA-Seq测序
Li C, et al. Characterization of skin ulceration syndrome associated microRNAs in sea cucumber Apostichopus japonicus by deep sequencing. (2012) Fish & Shellfish Immunology (IF= 3.034)

RNA-Seq转录组测序与分析
Two origins of blastemal progenitors define blastemal regeneration of zebrafish lower jaw. (2012) PloS ONE （IF =3.534）

基因调控网络分析
Gene Expression Profile of the Hippocampus of Rats Subjected to Chronic Immobilization Stress PloS ONE DOI（IF =3.534）

lncRNA调控网络分析
Dynamic Transcription of Long Non-Coding RNA Genes during CD4+ T Cell Development and Activation（IF =3.534）

表观组甲基化分析/illumina 450K芯片
Epigenomic analysis of lung adenocarcinoma reveals novel DNA methylation patterns associated with smoking. OncoTargets and Therapy. 2013,21(6:)1471-9 （IF= 1.342）

ChIP-Seq免疫组共沉淀测序分析
Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells. (2011). Mol Cell. （IF=14.464）

生物信息/芯片分析
The MicroArray Quality Control (MAQC) Consortium MAQC-II Project: A comprehensive survey of common practices for the development and validation of microarray-based predictive models. (2010) Nature（IF=42.351）

生物信息/蛋白相互作用预测
Global protein interactome exploration through mining genome-scale data in Arabidopsis thaliana. BMC Genomics.(2010). BMC Genomics (IF= 4.041)

生物信息/组蛋白修饰
Nucleosome structure incorporated histone acetylation site prediction in Arabidopsis thaliana. BMC genomics. (2010). BMC Genomics (IF=4.041)

文献挖掘/蛋白相互作用预测
Integrative identification of Arabidopsis mitochondrial proteome and its function exploitation through protein protein interaction network. (2009). PLOS ONE (IF=3.534)

文献挖掘/数据库构建/蛋白相互作用
AtPID: Arabidopsis thaliana protein interactome database–an integrative platform for plant systems biology. (2008). Nucleic Acids Research (IF= 8.808)

文献挖掘/数据库构建/蛋白相互作用预测
Construction of a chloroplast protein interaction network and functional mining of photosynthetic proteins in Arabidopsis thaliana. (2008) Cell Research (IF= 11.981)

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